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Overview

Magellon is a cryo-EM workflow platform. It ties together a FastAPI core service, a React front-end, and a growing library of processing plugins (CTF estimation, motion correction, particle picking) behind a shared job model.

  • Core service — FastAPI + SQLAlchemy. Owns the plugin registry, job persistence, and Socket.IO progress streaming.
  • Plugins — Python packages under CoreService/plugins/<category>/<name>. Each exposes Pydantic input/output schemas and a lifecycle the framework drives.
  • Front-end — React 19 + MUI 7. The plugin runner generates forms from each plugin’s JSON Schema, so adding a plugin does not require UI work.
  • Persistence — MySQL (via Alembic migrations). Jobs and their settings are stored as JSON columns so schema evolution stays cheap.
  • Transport — REST for control, Socket.IO for live progress.